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Effects of Concentrated Ambient Particles and Diesel Engine Exhaust on Allergic Airway Disease in Brown Norway Rats
Report #: 145, Publication Type: Research Reports Author: Harkema, Jack R, James G. Wagner, Norbert E. Kaminski, Masako Morishita, Gerald J. Keeler, Jacob D. McDonald, and Edward G. Barrett, 2009-11-30 Order this Publication About This Publication Please scroll down to download the report or HEI statement (a short synopsis).
This report describes a study to investigate the suggested association between exposure to traffic-derived pollution and increases in symptoms of airway diseases, including exacerbation of asthma. Dr. Jack Harkema and colleagues assessed the effects of two pollutant mixtures, concentrated ambient particles (CAPs) and diesel exhaust, on airway inflammatory and allergic responses in a rodent model of asthma. The study was one part of an HEI 3-study program of animal and human research on these important questions.Free Downloads:
Title Description Size 2/04/2010. Press version. Includes a Critique by the HEI Health Review Committee. 1782 kb 11/30/2009. PDF Format 108 kb
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